SC - 1247 | Superbugs: An Arms Race Against Bacteria

William Hall

Antibiotics are powerful drugs that can prevent and treat infections, but they are becoming less effective as a result of drug resistance. Resistance develops because the bacteria that antibiotics target can evolve ways to defend themselves against these drugs. When antibiotics fail, there is very little else to prevent an infection from spreading.

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SC - 1246 | Drug Resistance in Bacteria, Fungi, Malaria, and Cancer

Gunjan Arora, Andaleeb Sajid, Vipin Chandra Kalia (eds.)

This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome.

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SC - 1501 | Netter's Illustrated Pharmacology Updated Edition with Student Consult Access, 1ed

This updated edition of Netter's Illustrated Pharmacology allows you to take a distinct visual approach to understanding both the basic science and clinical applications of pharmacology.Designed to be compatible and used in conjunction with other pharmacology resources, this medical reference book offers a vivid, uniquely effective visual presentation of the pharmacodynamic relationship between drugs and the human body. And with the new addition of Student Consult online access, Netter's Illustrated Pharmacology is even more convenient than ever before!

• Available online for the first time! Search the full contents of Netter's Illustrated Pharmacology no matter what your location with convenient access to Student Consult.
• Visually grasp the most important principles in pharmacology with succinct, easy-to-understand presentations of introductory pharmacologic principles based on classic images by Frank Netter, as well as dynamic new illustrations from other talented medical artists.
• Learn how drugs are used to treat specific disorders in the body, as well as their effects on a particular site, with a format divided by organ system and full-color illustrations of the systems themselves.
• Access in-depth guidance on the must-know elements of each pharmacologic principle with clear, concise notes located beneath the corresponding image.

Authors:
Robert B. Raffa PhD, Scott M. Rawls PhD, Elena Portyansky Beyzarov PharmD

Year: 2014

Publisher: Saunders Elsevier
Language: english
ISBN: 978-0-323-22091-0

ID: SC - 1501

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264 - Gender and Migraine

Gender and Migraine (Headache) by Antoinette Maassen van den Brink (Editor), E. Anne MacGregor (Editor)

This book focuses on the influence of sex and gender in migraine, presenting new insights in basic science as well as their clinical relevance.

As migraine is roughly three times more common in women than in men, and also highly depends on hormonal milestones - such as menarche, menstruation, pregnancy and menopause - particular attention is devoted to the role of female sex hormones in this disease.

The first chapters present general data on gender-related differences in migraine such as epidemiology, comorbidities and related risks. Furthermore, while several chapters focus on the role of female sex hormones in migraine-triggering mechanisms at a basic scientific level (e.g. cranial circulation), ample attention is also paid to the clinical relevance of such mechanisms and to the best clinical treatment for migraine patients.

As the first book entirely devoted to this topic, it will be of interest to researchers and practitioners in the fields of neurology, internal medicine, endocrinology, physiology and pharmacology.

2019 | ISBN: 3030029875 |  ID - 264

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268 - Don't Eat This If You're Taking That

Don't Eat This If You're Taking That: The Hidden Risks of Mixing Food and Medicine by Madelyn Fernstrom CNS (Author), John Fernstrom (Author)

NBC Today show nutrition and diet guru Madelyn Fernstrom and award-winning neuroscientist and pharmacologist John Fernstrom -partnering with AARP- present the ultimate guide to food and medicine interaction.

Millions of Americans take prescription drugs to treat diabetes, high blood pressure, heart disease, or other conditions. But beware: The foods you eat and the medications you take could be working against each other.

Don't Eat This If You're Taking That takes the mystery out of food and medication interactions. This easy-to-use guide details foods that can interfere with the action of the medication-whether taken for the short or long term. In this book, readers can easily find a medication, see what foods to avoid, and make smart swaps.

We all believe a diet rich in colorful fruits and vegetables, lean proteins, whole grains, and low-fat dairy products is part of healthy eating-right? Not always. Dr. Fernstrom explains exactly what foods to avoid when and why. For instance,

If you're taking cholesterol medicine, you should cut out-or cut down on-grapefruit.
On a blood thinner? Avoid dark green veggies.
If you're on thyroid medication, nix the soy.
And more small diet changes with big health payoffs!

As an added bonus, each chapter offers a "Dietary Supplements Alert" box, providing the most up-to-date information on interactions with vitamins, minerals, and other dietary supplements.

With this concise, scientifically based guide, consumers can easily personalize their eating plan to work with, not against, their medications.

2017 | ISBN: 1632204525, 151071538X |  ID - 268

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272 - Practical Manual of Dispensing Pharmacy

Practical Manual of Dispensing Pharmacy by Nilimanka Das (Author)

Pharmaceutical Science is one such realm of novel thoughts translating into technologies to improve the quality of life. In the vicinity of Pharmaceutical Science, preparation and dispensing of pharmaceutical products has occupied a vast space.

Hence, attempt has been made to delve further into the subject of dispensing pharmacy with certain products of significance to the undergraduate students of pharmacy. This book may also be a helping hand for the postgraduate students and other readers. This book consists of 60 numbers of practicals.

Every single practical is designed and represented such a way so that the student's fraternity can understand the real objective behind the practical. The detailed theory of practicals will enlighten the students with facts and the science behind it. The book contains compendia and extemporaneous products dispensing with suitable labeling, packaging and storage instructions. The book also contains the precaution that need to be exercised during compounding of such products.

This book is supported by appendices containing commonly used Latin terms used in prescriptions, dosage calculation and containers & labeling instructions. At the end of every practical few important questions are provided for student's ready reference.

2017 | ISBN: N/A | ASIN: B07NT2CDYB |  ID - 272

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276 - Samuels's Manual of Neurologic Therapeutics

Samuels's Manual of Neurologic Therapeutics by Martin Samuels (Author), Allan H. Ropper MD (Author)

The best-selling Samuels's Manual of Neurologic Therapeutics is a practical, accessible handbook for the diagnosis and treatment of neurologic disorders.

Completely updated to reflect the most recent developments in the field, the book features a concise, intuitive outline format that makes today's best approaches easy to find and apply.

- Implement the current strategies to combat neurological diseases. Highlights include new pharmacologic and non-pharmacologic treatments for seizures; new molecular techniques and personalized approaches to neurologic cancers; new approaches for treating pain; the most recent intra-arterial therapies for acute stroke; and new treatments for neurologic infectious diseases.

- Manage benign autoimmune conditions with the aid of a new chapter that discusses diagnosis via serological testing as well as therapies involving immune modulation.

- Treat patients in resource-limited environments, thanks to a new chapter that focuses on cost-effective management options.

- Locate the information you need quickly through accessible and well-organized chapters and an outline format.

2017 | ISBN: 1496360311 |  ID - 276

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282 - Oxford Case Histories in Anaesthesia

Oxford Case Histories in Anaesthesia by Jon McCormack (Editor), Keith Kelly (Editor)

Based around the core curriculum for specialist trainees, Oxford Case Histories in Anaesthesia contains over 60 clinical cases compiled by expert consultants.

The cases comprehensively cover all sub-specialties and a broad range of variations that occur in normal and abnormal physiology, pharmacology and pathology, as well as patient age. The cases have been selected with reference to the revised Curriculum for a Certificate of Completion of Training in Anaesthesia set by the Royal College of Anaesthetists.

Each case begins with clear learning outcomes and is mapped to the CCT matrix, greatly aiding those revising for the Final FRCA examination. The cases are presented with a background to the subject area, and a summary of the history and examination findings with relevant investigation results. This is followed by several questions on clinically important aspects of the case with answers and detailed discussion, particularly of the differential management options. Further reading at the end of each case aids future study.

As well as those preparing for the Final FRCA, this book will also be of interest for post-fellowship trainees on specialty attachments and those who occasionally have to anaesthetize out with their normal field of practice, for example in subspecialty emergencies or whilst awaiting retrieval teams to arrive for transfer to tertiary care centres.

2015 | ISBN: 0198704860 |  ID - 282

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306 - Glutathione (Oxidative Stress and Disease) by Leopold Flohe

This is the first serious attempt to synthesize all that became known of glutathione over the last three decades. The book contains an update of glutathione biosynthesis with special emphasis on its regulation in adaptive stress responses.

Other chapters review glutathione transport systems and glutathione peroxidases and their differences in substrate specificities and localization.

Further contributions center on the diversified roles of different glutathione-S-transferases and the roles of nitrosoglutathione and glutaredoxins - a subfamily of redoxins.

The book closes with discussions of the analogous or homologous thiol metabolism in pathogens and the potential suitability of involved enzymes as drug targets.

Key selling features:

- Summarizing the way glutathione is involved in stress responses
- Compiling the multiple ways glutathione affects inflammatory responses
- Disclosing how glutathione dampens programmed cell death such as ferroptosis
- Exploring the enigma of how enzymes accelerate glutathione-dependent processes
- Discussing how detoxification and redox regulation is mediated by glutathionylation
- Reviewing the ways glutaredoxins catalyze protein disulfide reduction
- Highlighting the medical impact of glutathione-related metabolic pathways
- Illustrating the role thiol metabolism of pathogens might play in drug discovery

2018 | ISBN: 0815365322 |  ID - 306

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307 - Mobile Microspies

Mobile Microspies: Particles for Sensing and Communication by Michael Köhler (Author)

On the one hand, particle-based sensing techniques are driven by new technologies for preparing and measuring micro- and nanoparticles and by a fascination of the possibilities for design and functionalization of all specificities in structure shapes and behavior of these tiny objects ...

On the other hand, there evolves a fast-growing need for new sensing and communication paths for medicine, biotechnology, and analytical science, as well as for new and efficient information transfer and storage systems. No longer are particles regarded only as special types of materials. However, we have a better understanding of how they are bridging the gap between material and system, between structure and function.

Although there are numerous books on micro- and nanoparticles and on sensors, there is, to the best of my knowledge, no book focusing on the general concept of particles as mobile microtransducers.

This book clarifies that signal-transducing particles should be regarded as functional elements, as part of a system, not simply as special materials. It introduces concepts of bead-base sensing and 'mobile spies' at the micro- and nanoscale and gives a representative overview of the variety of particle-based sensing.

The state of the art in the development of particles as mobile spies for communication and information management allows us to speculate about future particle-based components and systems in a completely sustainable world economy.

In addition, the book reports on a fast-evolving technical field, which is a typical example of the required convergence of technical strategies and mechanisms in living nature, and would make a great reference for professionals and students of chemistry, biochemistry, biology, pharmacy, medicine, agriculture, mechatronics, informatics, materials science, and systems engineering.

2019 | ISBN: 9814800147 |  ID - 307

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312 - Ion Channel Drug Discovery by Brian Cox, Martin Gosling

Ion channel drug discovery is a rapidly evolving field fuelled by recent, but significant, advances in our understanding of ion channel function combined with enabling technologies such as automated electrophysiology.

The resurgent interest in this target class by both pharmaceutical and academic scientists was clearly highlighted by the over-subscribed RSC/BPS 'Ion Channels as Therapeutic Targets' symposium in February 2009.

This book builds on the platform created by that meeting, covering themes including advances in screening technology, ion channel structure and modelling and up-to-date case histories of the discovery of modulators of a range of channels, both voltage-gated and non-voltage-gated channels.

The editors have built an extensive network of contacts in the field through their first-hand scientific experience, collaborations and conference participation and the organisation of the meeting at Novartis, Horsham, increased the network enabling the editors to draw on the experience of eminent researchers in the field. Interest and investment in ion channel modulation in both industrial and academic settings continues to grow as new therapeutic opportunities are identified and realised for ion channel modulation.

This book provides a reference text by covering a combination of recent advances in the field, from technological and medicinal chemistry perspectives, as well as providing an introduction to the new 'ion channel drug discoverer'. The book has contributions from highly respected academic researchers, industrial researchers at the cutting edge of drug discovery and experts in enabling technology. This combination provides a complete picture of the field of interest to a wide range of readers.

2014 | ISBN-10: 1849731861 |  ID - 312

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334 - Chaperokine Activity of Heat Shock Proteins

Chaperokine Activity of Heat Shock Proteins by Alexzander A. A. Asea (Editor), Punit Kaur (Editor)

Chaperokine, is a term that describes the unique function of extracellular heat shock protein (eHsp) as both chaperone and cytokine. The cellular consequence of binding and signaling of eHsp is the stimulation of a potent and long lasting immune response...

eHsp induces a plethora of immune responses including the release of bioactive mediators like cytokines, chemokines, nitric oxide, apotogenic mediator, stimulation of the innate and adaptive immune response, migration and maturation of dendritic cells (DC) and the enhancement of natural killer cell-mediated cellular cytotoxicity.

The book Chaperokine Activity of Heat Shock Proteins provides the most comprehensive review on contemporary knowledge on the chaperokine activity of heat shock proteins (HSP) in biology and medicine. Using an integrative approach to understanding the chaperokine activity of HSP, the contributors provide a synopsis of novel mechanisms, signal transduction pathways and how the principles of the chaperokine activity of HSP has been harnessed for therapeutic gain.

To enhance the ease of reading and comprehension this book has been subdivided into various section, including; Section I, reviews current progress on our understanding of Immunological and Inflammatory Responses; Section II, evaluates the role of Physiological Responses and Section III, focuses the reader on the Therapeutic Approach.

Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future.

The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychologists, Human Physiology, Zoologists, Botanists, Biotechnology, Molecular Medicine, Infectious Diseases Experts, Pathologists, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

2019 | ISBN-10: 3030022536 |  ID - 334

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355 - Reviews of Physiology, Biochemistry and Pharmacology, Vol. 175

Reviews of Physiology, Biochemistry and Pharmacology, Vol. 175 by Bernd Nilius (Editor), Pieter de Tombe (Editor), Thomas Gudermann (Editor), Reinhard Jahn (Editor), Roland Lill (Editor)

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.

2018 | ISBN: 3319952870, 3030070093 | ID - 355

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397 - Multi-Target Drug Design Using Chem-Bioinformatic Approaches

Multi-Target Drug Design Using Chem-Bioinformatic Approaches (Methods in Pharmacology and Toxicology) by Kunal Roy (Editor)

This detailed book showcases recent advances in computational design of multi-target drug candidates involving various ligand and structure-based strategies.

Different chem-bioinformatic modeling strategies that can be applied for design of multi-target drugs as well as important databases and web servers in connection with multi-target drug design are also featured in this collection.

Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of key implementation advice that will aid researchers greatly in their laboratory pursuits.

Authoritative and practical, Multi-Target Drug Design Using Chem-Bioinformatic Approaches seeks to aid all scientists working in the field of drug discovery research.

2018 | ISBN: 1493987321 | ID - 397

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400 - Cumulative Index of Heterocyclic Systems

Cumulative Index of Heterocyclic Systems (Chemistry of Heterocyclic Compounds: A Series Of Monographs) by Desmond J. Brown (Editor), Edward C. Taylor (Editor), Jonathan A. Ellman (Editor)

The Cumulative Index of Systems Reviewed in the Chemistry of Heterocyclic Compounds is a collection of data for the approximately 2700 systems reviewed therein that serves as a useful guide to locating information in this well established and reputable series.

The Cumulative Index also contains a complete list of books in the series showing author(s), title, date of publication, and all chapter headings. It is useful to professionals and advanced graduate students in synthetic organic chemistry, in academia, government, and industries including pharmaceuticals, fine chemicals, and agriculture.

2008 | ID - 400

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370 - Boh's Pharmacy Practice Manual

Boh's Pharmacy Practice Manual: A Guide to the Clinical Experience Fourth Edition by Susan M. Stein D.H.Ed. M.S. B.S.Pharm. (Editor)

Thoroughly revised for its fourth edition, this pocket-sized manual is created for students to use during rotations in PharmD programs, and also provides a wealth of crucial information for new practitioners.

Boh's is the clinical clerkship manual designed specifically for pharmacy students and pharmacists new to the field, helping students and new practitioners move from dispensing medications to establishing relationships with patients and improving the understanding of pharmacotherapeutics in a patient-centered setting.

2015 | ISBN: 1451189672 | ID - 370

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378 - Pharmacy Technician Exam 3rd Edition by Learning Express Editors

The updated edition of LearningExpress's top-selling Pharmacy Technician Exam covers everything tested on the Pharmacy Technician Certification Examination (PTCE), the certification test for this lucrative and growing career. There are approximately 350,000 pharmacy technicians across the United States. All aspiring pharmacy technicians, in both retail pharmacies and other institutions such as hospitals or research labs, need to pass this exam in order to be successful in the field.

This guide includes everything students need to pass the challenging exam, including:

Access to THREE full-length practice exams with detailed answer explanations
A complete review of the career, including top schools, requirements, recommended courses, and professional resources
A complete review of pharmacy science and math, medications, dosages, pharmacy law, state and federal regulations, and more
A glossary of key pharmacy tech terms

2017 | ISBN: 161103079X | ID - 378

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373 - Computational Methods for Drug Repurposing

Computational Methods for Drug Repurposing (Methods in Molecular Biology) by Quentin Vanhaelen (Editor)

This detailed book explores techniques commonly used for research into drug repurposing, a well-known strategy to find alternative indications for drugs which have already undergone toxicology and pharma-kinetic studies but have failed later stages during the development, via computational methods.

Thereby, it addresses the intense challenges of identifying the appropriate type of algorithm and relevant technical information for computational repurposing. Written for the highly successful Methods in Molecular Biology series, the authors of each chapter use their experience in the field to describe the implementation and successful use of a specific repurposing method thus providing lab-ready instruction.

Authoritative and practical, Computational Methods for Drug Repurposing serves as an ideal guide to researchers interested in this vital area of drug development.

2018 | ISBN: 1493989545 | ID - 373

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426 - Data Integrity and Data Governance

Data Integrity and Data Governance: Practical Implementation in Regulated Laboratories by R D McDowall (Author)

Data integrity is the hottest topic in the pharmaceutical industry. Global regulatory agencies have issued guidance, after guidance after guidance in the past few years, most of which does not offer practical advice on how to implement policies, procedures and processes to ensure integrity.

These guidances state what but not how. Additionally, key stages of analysis that impact data integrity are omitted entirely.

The aim of this book is to provide practical and detailed help on how to implement data integrity and data governance for regulated analytical laboratories working in or for the pharmaceutical industry. It provides clarification of the regulatory issues and trends, and gives practical methods for meeting regulatory requirements and guidance. Using a data integrity model as a basis, the principles of data integrity and data governance are expanded into practical steps for regulated laboratories to implement. The author uses case study examples to illustrate his points and provides instructions for applying the principles of data integrity and data governance to individual laboratory needs. This book is a useful reference for analytical chemists and scientists, management and senior management working in regulated laboratories requiring either an understanding about data integrity or help in implementing practical solutions. Consultants will also benefit from the practical guidance provided.

2019 | ISBN: 178801281X | ID - 426

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428 - Transition Metal Catalyzed Oxidative Cross-Coupling Reactions

This book is a comprehensive text covering the research and development trends in the booming field of transition metal catalyzed oxidative cross-coupling reactions. Oxidative cross-coupling reaction is a new method to forming chemical bonds besides the traditional cross-coupling reactions.
This book provides the answers to how this coupling reaction occurs and what its advantages are.

The palladium, copper and iron catalyzed oxidative cross-coupling reactions as the main focuses of interest are described in detail. The oxidative cross-coupling reactions catalyzed by other metals and transition-metal-free oxidative coupling reactions are also introduced.This book provides a useful reference source for researchers and graduates in the field of transition metal catalyzed coupling reactions. It is also valuable to researchers working in pharmaceutical companies, fine organic chemical companies, and etc.

ISBN: 3662581027 | 2019 | ID - 428

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